KMID : 0374920110320010161
|
|
Inje Medical Journal 2011 Volume.32 No. 1 p.161 ~ p.170
|
|
Two cases of acute renal failure associated with acute viral hepatitis A
|
|
Hong Su-Min
Park Kyung-Sik Park Il-Kwon Sohn Hyung-Rae Koo Ho-Seok Koh Haeng-Il
|
|
Abstract
|
|
|
Hepatitis A is a mild, self-limiting disease of the liver, critical complications of which, such as acute kidney injury, are rare. Two cases of patients with acute hepatitis A who had an acute renal failure complication are reported herein. The first case is that of a 30-year-old man who showed up at the author¡¯s hospital complaining of fever and myalgia. His laboratory tests upon his admission showed 9,520 lU/L of aspartate transaminase, 5,600 lU/L of alanine transaminase, 31.9 mg/dL of blood urea nitrogen, and 5.5 mg/dL of creatinine, and he was positive for the Anti-HAV IgM antibody. Upon his admission, supportive treatment was started, which included fluid therapy. The laboratory tests on the next day showed 53 mg/dL of blood urea nitrogen, 9.9 mg/dL of creatinine, and lower urine output per day. Renal replacement therapy was performed only once. A renal biopsy was performed and the result was Acute Tubular Necrosis (ATN). The patient recovered from acute renal failure without sequela. In the second case, a 35-year-old man complained of fever and abdominal pain. His laboratory tests upon his admission showed 8,570 lU/L of aspartate transaminase, 4,510 lU/L of alanine transaminase, 16 mg/dL of blood urea nitrogen, and 1.19 mg/dL of creatinine, and he was positive for the Anti-HAV IgM antibody. He experienced acute renal failure and recovered after two-time renal replacement therapy. The result of the renal biopsy was Acute Tubular Necrosis and C1q nephropathy.
|
|
KEYWORD
|
|
Acute kidney injury, Hepatitis A, Dialysis
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|